Isotopically Labeled Compounds
Medchemexpress LLC Colchicine-d3 | 1217625-62-1 | 99.2% | 402.46 | 1 MG
Colchicine-d3 is the deuterium labeled Colchicine. It acts as a tubulin inhibitor and a microtubule disrupting agent, effectively inhibiting microtubule polymerization with an IC50 of 3 nM. This compound also functions as a competitive antagonist of the α3 glycine receptors (GlyRs).
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits microtubule polymerization
- Competitive antagonist of α3 glycine receptors
Medchemexpress LLC Heptadecanoic acid-d33 | 352431-41-5 | 303.65 | 50 MG
Heptadecanoic acid-d33 is a deuterium labeled odd chain saturated fatty acid (OCS-FA). It is associated with several diseases, including coronary heart disease, prediabetes, type 2 diabetes, and multiple sclerosis. This product is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules as tracers
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Cambridge Isotope Laboratories DOCOSANOIC ACID (12,12,13,13-D4, 98%), 0.25 G
DOCOSANOIC ACID (12,12,13,13-D4, 98%), 0.25 G
Medchemexpress LLC Pregn-4-ene-3,20-dione-d9 | 15775-74-3 | MFCD01317491 | 99.7% | 323.52 | C21H21D9O2 | 10 MG
Progesterone-d9 is a deuterium-labeled analogue of the endogenous steroid hormone progesterone, provided as a solid for research use. It is intended for use as a tracer and internal standard in quantitative analytical methods and pharmacokinetic or metabolic studies.
- Deuterium-labeled tracer and internal standard for NMR, GC-MS, and LC-MS.
- Chemical formula C21H21D9O2.
- Molecular weight 323.52 g/mol.
- Supplier-listed purity ~99.7% (verify for critical use).
- Appearance: white to light yellow solid.
- Solubility: DMSO 50 mg/mL; may require sonication and warming.
- Storage: powder at -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Typical pack size: 10 mg.
Medchemexpress LLC Valproic acid-d15 | 362049-65-8 | MFCD01861597 | 99.8% | 159.30 | C8HD15O2 | 5 MG
Valproic acid-d15 is a deuterium-labeled stable isotope of valproic acid used as an internal standard and tracer for analytical, pharmacokinetic, and metabolic studies. It is supplied as a high-purity liquid suitable for LC-MS/MS and other mass spectrometry applications.
- High isotopic enrichment with 99.8% purity.
- Chemical formula C8HD15O2; molecular weight 159.30.
- Available in small quantities for analytical workflows (5 MG).
- Suitable for use as an internal standard in quantitative assays.
- Storage recommendation: -20°C for long-term stability.
Cayman Chemical LInzolId-d3 1mg
An internal standard for the quantification of linezolid by GC- or LC-MS
Medchemexpress LLC Salcaprozate-d4 sodium (SNAC-d4 sodium) | 203787-91-1 | 99.7% | 305.34 | 1 MG
Salcaprozate-d4 (sodium) is a deuterated labeled Salcaprozate (sodium). Salcaprozate sodium (SNAC) is an oral absorption promoter with potential as a delivery agent for oral forms of heparin and insulin. It can increase passive transcellular permeation across small intestinal epithelia by increasing lipophilicity from non-covalent macromolecule complexation.
- Deuterated labeled compound.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into the drug molecule.
- Potential to affect the pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories Estradiol (3 4-13C2 99%) 100 ug/mL in acetonitrile 1 2 mL
Estradiol (3 4-13C2 99%) 100 ug/mL in acetonitrile 1 2 mL
Medchemexpress LLC DL-Alanine-d3 | 53795-94-1 | 25 MG
DL-Alanine-d3 is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. It is used as a reducing and capping agent with silver nitrate aqueous solutions for nanoparticle production, and for research of transition metal chelation. DL-alanine is also a sweetener and plays a role in the glucose-alanine cycle between tissues and liver.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Fumaric acid-d2 | 24461-32-3 | MFCD00144378 | 99.0% | 118.08 g/mol | C4H2D2O4 | 10 MG
Fumaric acid-d2 is the deuterium-labeled isotopologue of fumaric acid used as a stable isotope reference standard and tracer for analytical and metabolic research. Supplied as a high-purity solid, it is suitable for mass spectrometry and NMR applications and is provided in small laboratory pack sizes for convenience.
- High purity suitable for analytical use.
- Deuterium-labeled (d2) isotopologue for tracer studies.
- White to off-white solid powder with specified storage conditions.
- Soluble in DMSO at ≥100 mg/mL for solution preparation.
- Available in multiple small pack sizes for laboratory workflows.
Medchemexpress LLC Uric acid-15N2 | 62948-75-8 | 99.9% | 5 MG
Uric acid-15N2 is the 15N labeled Uric acid. Uric acid is an important antioxidant and scavenger of oxygen radicals, contributing to the stability of blood pressure and antioxidant stress. It removes reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, which helps inhibit lipid peroxidation.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis.
- Stable heavy isotopes have been incorporated into molecules for quantitation during the development process.
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of substances.
Medchemexpress LLC Thioridazine-d3 hydrochloride | 1189928-36-6 | 98.25% | 5 MG
Thioridazine-d3 hydrochloride is a deuterium-labeled Thioridazine, acting as an antagonist of dopamine receptor D2 family proteins with potent antipsychotic and anti-anxiety activities. It also inhibits PI3K-Akt-mTOR signaling pathways, exhibiting an anti-angiogenic effect, and induces antiproliferative and apoptosis effects in various cancer cells, specifically targeting cancer stem cells (CSCs).
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS methods
Medchemexpress LLC D-Glucose-13C-5 | 106032-62-6 | 98.0% | 100 MG
D-Glucose-13C-5 is the 13C labeled D-Glucose, a monosaccharide and important carbohydrate in biology. It acts as a carbohydrate sweetener, a vital component of general metabolism, and a critical signaling molecule involved in cellular metabolic status and biotic and abiotic stress responses.
- Functions as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Important carbohydrate in biological processes
- Acts as a carbohydrate sweetener
- Critical component in general metabolism
- Involved in cellular metabolic status signaling
- Participates in biotic and abiotic stress responses
Medchemexpress LLC Posaconazole-d5 | 1217785-83-5 | MFCD11977890 | 99.1% | 705.81 | 5 MG
Posaconazole-d5 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second-generation, triazole compound with antifungal activity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
